What is sterol


Sterol, Sterol, Stenol, unsaturated, tetracyclic secondary alcohols, which contain three linked cyclohexane rings and a cyclopentane ring as the basic structure. The saturated analogs of the sterols are called Stanol designated. Sterols are one from the C30-Sterol-derived group of biosynthetically formed compounds which are widespread as part of the cell membranes of eukaryotic organisms. Due to their long and flat shape, they support the stability of the cell membrane. The flat shape of the sterol is ensured by the presence of all ring molecules in the chair configuration with the trans position of the ring junctions, the 8β (H), 9α (H), 10β (CH3), 13β (CH3), 14α (H), 17α (H), 20R configuration. For this reason, only this configuration is formed biosynthetically, although a large number of chiral centers are present and theoretically more than 250 diastereomers (stereoisomerism) would be possible. Since isomerizations occur preferentially at the C-14-, C-17- and at the C-20-carbon atom during the diagenesis, the biologically formed configuration of the sterol becomes 14α (H), 17α (H), 20R-configuration or short αα (20R) configuration. During the diagenesis, the corresponding sterane is formed from the sterols. A common sterol is cholesterol. [SB]